KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AMBRA1
All Species:
19.09
Human Site:
S1149
Identified Species:
52.5
UniProt:
Q9C0C7
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9C0C7
NP_060219.2
1298
142507
S1149
A
S
G
E
D
A
L
S
R
I
Q
R
L
M
A
Chimpanzee
Pan troglodytes
XP_001163113
1208
132805
E1067
R
I
Q
R
L
M
A
E
G
G
M
T
A
V
V
Rhesus Macaque
Macaca mulatta
XP_001112256
1298
142465
S1149
A
S
G
E
D
A
L
S
R
I
Q
R
L
M
A
Dog
Lupus familis
XP_540754
1211
132916
T1070
L
M
A
E
G
G
M
T
A
V
V
Q
R
E
Q
Cat
Felis silvestris
Mouse
Mus musculus
A2AH22
1300
142860
S1150
G
S
G
E
D
A
L
S
R
I
Q
R
L
M
A
Rat
Rattus norvegicus
NP_001127813
1300
142989
S1150
G
S
G
E
D
A
L
S
R
I
Q
R
L
M
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233289
1300
142720
S1152
A
S
G
E
D
A
V
S
R
I
Q
R
L
M
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001342016
1003
110813
E862
P
K
Q
L
S
V
S
E
H
L
K
G
D
T
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797133
781
86047
I640
H
N
D
A
S
V
D
I
S
S
D
R
R
L
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.9
99
89.8
N.A.
95.6
95.9
N.A.
N.A.
83
N.A.
47.6
N.A.
N.A.
N.A.
N.A.
27.6
Protein Similarity:
100
93
99.3
90.7
N.A.
97.1
97.3
N.A.
N.A.
88.9
N.A.
58.7
N.A.
N.A.
N.A.
N.A.
37.6
P-Site Identity:
100
0
100
6.6
N.A.
93.3
93.3
N.A.
N.A.
93.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
6.6
100
33.3
N.A.
93.3
93.3
N.A.
N.A.
100
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
0
12
12
0
56
12
0
12
0
0
0
12
0
67
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
12
0
56
0
12
0
0
0
12
0
12
0
0
% D
% Glu:
0
0
0
67
0
0
0
23
0
0
0
0
0
12
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
23
0
56
0
12
12
0
0
12
12
0
12
0
0
0
% G
% His:
12
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% H
% Ile:
0
12
0
0
0
0
0
12
0
56
0
0
0
0
0
% I
% Lys:
0
12
0
0
0
0
0
0
0
0
12
0
0
0
12
% K
% Leu:
12
0
0
12
12
0
45
0
0
12
0
0
56
12
0
% L
% Met:
0
12
0
0
0
12
12
0
0
0
12
0
0
56
0
% M
% Asn:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
23
0
0
0
0
0
0
0
56
12
0
0
12
% Q
% Arg:
12
0
0
12
0
0
0
0
56
0
0
67
23
0
0
% R
% Ser:
0
56
0
0
23
0
12
56
12
12
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
12
0
0
0
12
0
12
0
% T
% Val:
0
0
0
0
0
23
12
0
0
12
12
0
0
12
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _